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Ozempic face, loss of butt muscles, sagging tissues, loss of strength, and constipation are just some of the effects being reported

Introduction Once-weekly semaglutide 1 mg is a novel glucagon-like peptide 1 receptor agonist (GLP-1 RA) that, in the SUSTAIN clinical trials, has demonstrated greater reductions in glycated haemoglobin (HbA1c) and body weight than the other GLP-1 RAs exenatide extended-release (ER) 2 mg, dulaglutide 1.5 mg and liraglutide 1.2 mg

GLP-1 RAs provide sustained central and peripheral GLP-1R activation that blunts appetite via hypothalamusvagusNTS circuits, improves metabolic health, and may reduce alcohol and other substance-related craving and reward signals.

This article has been prepared using available research on metabolic therapies and retatrutide-based treatments

Taking a GLP-1 medication like semaglutide alongside antidepressants is possible, but requires medical oversight to manage potential interactions and ensure both conditions receive proper support

As GLP-1 induced cutaneous reactions are diverse, diagnosis requires clinical suspicion, thorough history-taking, and supportive histopathological findings when available