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Description
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Background: The evidence on berberine stimulating the secretion of GLP-1 in intestinal L cell has been studied
Metabolic Engineering activates the same pathway naturally without the side effects.
GLP-1R agonist 2 (compound 2) is an effective GLP-1R agonist that exerts its activating effect by forming hydrogen bonds with the Tyr42, Cys71, and Ser84 residues of GLP-1R
The current report aims to present an overview of current knowledge on GLP-1 RAs based on pragmatic review of the available clinical evidence
