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Preclinical studies have demonstrated that GLP-1R agonists can reduce the accumulation of amyloid plaques, a hallmark of Alzheimer's disease, and improve synaptic function

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Cells on poly-D-lysine-coated coverslips were loaded with 2 M Fura-2 AM (Thermo Fisher Scientific, Waltham, MA) at 37 C for 40 min in DMEM

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ALT: Alanine aminotransferase

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