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If you have significant and ongoing stomach pain, consult a doctor immediately, as this could be a sign of an inflamed pancreas (acute pancreatitis)

6 Weight regain after stopping is predictable STEP-1 Extension and STEP-4 both show that most weight lost is regained within 612 months once the drug is discontinued

For weight loss that may have stalled on tirzepatide, the resources about plateaus on GLP-1 therapy provide useful framing that applies regardless of which specific compound is involved

Syringes are required for administration

But now a new generation of medications has arrived, based on a better understanding of the biological underpinnings of obesity

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