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12 Several large, randomised trials have shown that GLP-1 RAs reduce major adverse cardiovascular events (MACE) compared with placebo

The structural design is tightly linked to the therapeutic profile, enabling the next generation of innovative GLP-1 RA drugs

METHODS The initial cohort comprised 179 individuals aged between 20 and 90 years, all diagnosed with type 2 diabetes and treated with a combination of dulaglutide and metformin

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