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1.3.5 EZH2 Enhancer of zeste homolog 2 (EZH2) catalyzes tri-methylation on histone 3 lysine 27 (H3K27me3), modification that represses gene expression, and is highly expressed in early gestation in neural precursor cells where it inhibits differentiation into neurons by blocking Wnt-signaling mediated activation of neural genes (Pereira et al., 2010

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