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The cross-talk between GLP-1 receptors in the liver and adipose tissue may play an important role in the prevention of hepatic steatosis

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105 Concerning the effect of these drugs on reproductive function, no significant difference was determined between GLP-1RAs and metformin for improving menstrual rate, decreasing serum testosterone, and free androgen index (FAI)
doi: Jastreboff AM, Aronne LJ, Ahmad NN, et al

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Melatonin improves local blood circulation and edema, and maintained the stability of the blood spinal cord barrier Studies have shown a reduction in the endothelial marker protein CD31 after SCI, suggesting damage to the blood-spinal cord barrier, and administration of melatonin increased the proportion of CD31-labeled vessels, suggesting that melatonin is effective in reducing the permeability of the blood-spinal cord barrier after SCI (Jing et al., 2017)