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Biological Plausibility: Why GLP-1 Agents May Reduce Risk The preventive signal observed with GLP-1 therapy is biologically plausible and likely multifactorial

Lhteenvuo M, Tiihonen J, Solismaa A, Tanskanen A, Mittendorfer-Rutz E, Taipale H

To sum up, here we report that in our novel two-session operant food intake paradigm, GLP-1 agonism differentially modulated homoeostatic, hedonic and anticipatory aspects of palatability-driven feeding behaviour
21 The most significant headwind will be felt by companies with a portfolio centered around food high in salt, sugar and fat, or alcohol

10.1002/jcsm.13445 101 PastaA.FacciorussoA.Plaz TorresM

March 2026
