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GLP-1R agonist 2 (compound 2) is an effective GLP-1R agonist that exerts its activating effect by forming hydrogen bonds with the Tyr42, Cys71, and Ser84 residues of GLP-1R

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Autoimmune thyroid disease (AITD), including Hashimoto thyroiditis and Graves disease, represents the most prevalent organ-specific autoimmunity and a major cause of thyroid dysfunction worldwide

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