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The analysis got me thinking a lot about the impact of adherence, which we know has been a challenge with these medications

23andMe Research Institute Study, Published in Nature, Identifies Genetic Predictors for GLP-1 Weight Loss Efficacy and Side Effects ...

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Recently, multiple case reports and studies indicating safety risks for these medications and their use in patients planning to undergo general anesthesia have been published, as retained gastric contents can lead to intraoperative aspiration

However, owing to their peptide-based composition, GLP-1RAs have traditionally required injectable administration, which undermines patient adherence, convenience, and long-term accessibility