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[27] investigated primary cultures of rat and human thyroid cells to assess the expression and function of GLP-1R in C cells

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However, according to the Liraglutide Effect and Action in Diabetes (LEAD) the reduction in systolic blood pressure of 3.6-6.7mmHg occurred within 2 weeks, which resulted prior to any substantial weight loss, this effect lasted throughout the entire 26-week trial 7