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Appeals for weight loss prescriptions face higher denial rates because many plans explicitly exclude weight loss medications regardless of medical necessity

This drowsiness can be stronger when combined with semaglutide, which may also cause mild fatigue in some people

Safety is a significant component in determining patient suitability for retatrutide

Semaglutide also isnt recommended while pregnant or breastfeeding, and the medication should be stopped at least 2 months before trying to conceive

References and Sources Neeland IJ, et al

Take metformin with or after meals to reduce stomach upset, and consider modified-release formulations if standard metformin causes persistent problems