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Without automatic substitution authority, the biosimilar company must deploy a commercial team equivalent in scale to a branded drug launch to specifically drive prescribers toward its product a cost structure that fundamentally undermines the low-price, high-volume generic business model

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The advent of long-acting analogs was therefore transformative

For men who want to conceive, this makes TRT a poor first choice when the low testosterone has an obesity-related metabolic cause that could be addressed directly