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Biomarkers: Modest Signals, Unclear Meaning While the EVOKE and EVOKE+ trials missed their primary and secondary clinical endpoints, they also collected an array of exploratory biomarkers to probe potential neuroprotective effects

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Notably, two participants exited the study due to anxiety (placebo group) and food aversion (liraglutide 1.2 mg group)

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Of these, 106 patients completed imaging at baseline and 52 weeks, enabling the analysis of left ventricular and atrial morphology and paracardiac adipose tissue