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GLP-1 peptides influence key metabolic pathways that regulate hunger, digestion, and blood sugar balance

Figure 4: Opportunities Outside of Diabetes and Obesity for Incretin Mimetics As mentioned earlier, NASH is an area that has attracted a high level of manufacturer attention, as the liver disease is associated with metabolic syndrome and represents an area of large commercial opportunity with significant unmet medical need

Clinical trials show 2040% of weight lost on semaglutide is lean mass

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For example, elevated liver enzymes may suggest underlying hepatic stress
