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Weight reduction is likely mediated by delayed gastric emptying, enhanced satiety, and reduced caloric intake 16

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These may include: Nausea, vomiting or diarrhoea (most common early on) Constipation Fatigue Mild increases in heart rate (similar to changes seen with GLP-1 medicines) Side effects were more frequent at higher doses (8 mg and 12 mg), but still rated mild to moderate overall

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Compounded semaglutide maintains the same active ingredient as branded formulations but is prepared in-pharmacy under state pharmacy board oversight, offering potential cost advantages