glp-1/gip dual agonist weight loss The Emerging Role of GLP-1 and GIP Receptor Agonists in Glycemic Management and Cardiovascular Risk Reduction Unveiling Tirzepatide's Therapeutic Spectrum: A
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Melanie Jay, who studies the treatment and prevention of obesity at NYU Langone Health

[DOI] [PMC free article] [PubMed] [Google Scholar] 71

The most common adverse effects were also gastrointestinal and dose-related and were partially mitigated with a lower starting dose (2 mg vs

Diabetes Obes Metab (2018) 20(1):2158

The glucose-dependent effects theory highlights that both hormones work in glucose-dependent ways but with different patterns

In the 2022 SURMOUNT-1 study published in NEJM, three doses of tirzepatide were compared with placebo (1:1:1:1) to determine effects on percent weight change over the course of 72 weeks