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doi: 10.1016/j.phrs.2022.106320

Agents such as oral semaglutide, orforglipron, CagriSema, retatrutide and maridebart cafraglutide have achieved unprecedented mean weight reductions, often exceeding 15% to 20% of baseline body weight in clinical trials.37 Clinicians must keep in mind that pharmacotherapy alone is not a cure for obesity

Irritable bowel syndrome: methods, mechanisms, and pathophysiology

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Generally, individuals who are classified as obese, with a body mass index (BMI) of 30 or higher, are considered suitable candidates for this treatment