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The F-statistic for the selected instrument variant (rs2268650) was 49.25, suggesting that there was little possibility of weak instrument bias in our study

Personalized weight management GLP-1 medications mimic natural hormones to regulate appetite and digestion

are the guarantors of this work and, as such, had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis

To induce weight loss, we employed the glucagon-like peptide 1 receptor (GLP-1R) agonist semaglutide and the neuropeptide Y receptor Y2 (NPY2R) agonist BI8271, which potentiates GLP-1R-mediated weight loss

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Patients often feel fuller sooner, have fewer cravings, and experience steadier energy levels throughout the day