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Description
Main body The influence of DPP-4 on bone metabolism occurs through two axes

9,50 A phase 3 trial is not yet registered but is anticipated to commence soon

Still, more research is needed on GLP-1s and testosterone to fully understand the effects, says Michael Wierschem, MD, urologist and founder of Dallas Men's Health

Last reviewed: June 26, 2026 Last updated: June 26, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

Lancet 2024, 404, 972987

These are typically the first signs of Semaglutides GLP-1 effectiveness and may be accompanied by early signs of weight loss
