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If you have diabetes and are taking a GLP-1 medication, make sure your ophthalmologist is aware of your medical history and current medications

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Patients using semaglutide in combination with sulfonylureas and insulins are at increased risk for hypoglycemia and may need to have their dose reduced when starting treatment with semaglutide

This captures cases where side effects were severe enough to warrant stopping treatment entirely

These agents act through multiple mechanisms, including direct cardioprotection, vasodilation, natriuresis, weight reduction, lipid profile improvement, anti-inflammatory effects, renal protection, reduction in plaque formation, and neurohormonal regulation [50]