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(NYSE: PFE) announced positive topline results from the phase 2b VESPER-3 study investigating monthly maintenance dosing of its fully-biased, ultra-long-acting, injectable GLP-1 receptor agonist (RA) PF3944 (MET-097i) in adults with obesity or overweight without type 2 diabetes

The x- and y-axes represent the two axes (Feature 1, Feature 2) onto which embeddings were dimensionally reduced using Uniform Manifold Approximation and Projection for visualization purposes

In this trial, the majority of subjects did not have established CVD at baseline, and the highly anticipated results from the trial will add to the body of evidence on the potential role for GLP-1RAs on CV risk reduction in a broad range of individuals with T2D [38]

What to Expect Beyond Month One: The Long-Term Trajectory Most semaglutide users experience their steepest weight loss between months two and six, with the rate of loss naturally slowing as they approach their body's adapted set point