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Similarly, in the United Kingdom Prospective Diabetes Study (UKPDS), only 34% of patients attained an A1c age 65) and patients with hepatic or renal disease are more likely to experience frequent and severe hypoglycemic reactions, particularly if the goals of therapy aim for inappropriately tight glycemic control (20)

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When beginning a GLP-1 treatment, it is important to begin on the lowest dose for that specific medication and only increase gradually to give the body time to adjust

Conclusion Dietary modification personalized to individual preferences and treatment goals (e.g., caloric deficits of 500 kcal/day), combined with structured physical activity (e.g., 150 minutes of moderate-to-vigorous exercise per week), produces additive benefits beyond GLP-1 therapy alone, enhancing weight loss, improving body composition, and reducing visceral fat and inflammation

Cette dernire rduit la glycmie en stimulant la scrtion d'insuline et en rduisant la scrtion de glucagon lorsque la glycmie est leve, quand on mange

doi: 10.1089/ars.2022.0016