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The medications have also been shown to reduce complications from kidney disease, improve heart and liver health, treat sleep apnea in overweight adults, and even protect the brain

doi: 10.1097/j.pain.0000000000001923

Obesity induces metabolic disturbances in adipose tissue, influencing the release of hormones, adipokines, inflammatory cytokines, growth factors, enzymes, and free fatty acids [12]

Weight loss and caloric restriction increase muscle proteolysis, providing amino acids for gluconeogenesis and acute-phase protein synthesis

doi: 10.1016/j.lfs.2020.117996 4 ScheltensPDe StrooperBKivipeltoMHolstegeHChtelatGTeunissenCEet al
