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Polyagonists in type 2 diabetes management

J Neurochem 135(6):12571271

Master transcription factors and mediator establish super-enhancers at key cell identity genes

With each of these conditions, longitudinal muscle contraction leads to esophageal shortening which leads to stretch of the phrenoesophageal membrane and displacement of the EGJ through the hiatus

Together, these hormones coordinate to regulate appetite, insulin and glucagon secretion, and nutrient metabolism, making them central to metabolic health