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Description
Why Excess Skin Develops After Rapid Weight Loss When you lose weight rapidly through GLP-1 medications, your skin cannot contract quickly enough to match your new body contours

Key Industry Developments: In October 2025 , Eli Lilly and Company achieved its fourth Phase III success with its oral GLP-1 receptor agonist, orforglipron, in type 2 diabetes trials

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The encouraging news: most people experience significant improvement over time

Additionally, both medications cause a delay in gastric emptying, which can result in stomach paralysis (gastroparesis), intestinal blockage (ileus), and other severe gastrointestinal side effects

Cardiovascular effects: Both agents may influence cardiovascular parameters
