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RANTES reduces glucose-stimulated GLP-1 secretion in vitro and in vivo in mice, by acting most probably through the intestinal glucose transporter SGLT1 (93)

[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Morroniside, a secoiridoid glycoside from Cornus officinalis, attenuates neuropathic pain by activation of spinal glucagon-like peptide-1 receptors

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This may be attributed to the stronger impact of GLP-1RAs on ventricular structure and function in this population [45]

Several animal studies and preliminary human trials have suggested that allulose may influence postprandial glucose responses and potentially affect GLP-1 secretion, though the evidence base remains limited and requires further validation

In rodents, these increases involve a dual pathways originating from both central nervous system and periphery with intact neural vagus transmission [52]