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Mitochondrial derived peptide literature, including work on MOTS c, has reinforced the value of linking signaling perturbations to downstream metabolic state signatures and stress response programs in model systems

Prebiotic oligofructose protects against high-fat diet-induced obesity by changing the gut microbiota, intestinal mucus production, glycosylation and secretion

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In the OASIS 4 phase 3 trial, oral semaglutide 25mg was studied in adults with overweight or obesity without type 2 diabetes

The intronic variant rs56159231 may influence ovarian cancer risk by disrupting Er and TCF11::MafG binding sites, modulating PLEKHM1 -mediated autophagy

A meta-analysis conducted on 17 studies observed a significant reduction in cancer risk with the use of metformin in patients with diabetes or without diabetes as compared to patients, not on metformin