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A separate randomized trial found that combining semaglutide with metformin outperformed metformin alone producing greater weight loss, improved insulin sensitivity, better cycle regularity, and higher rates of natural pregnancy

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If the temperature remained below 86F (30C), the medication should still be effective within the 56-day usage period

Genetic variation in GLP-1 receptor (GLP1R) and GIP receptor (GIPR) genes influences receptor sensitivity and gastric response

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