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Specific to cardiovascular-related death, ELIXA and SUSTAIN-6 trials showed similar performance relative to the placebo [ HR = 0.98 (95% CI 0.781.22) and HR = 0.98 (95% CI 0.651.48), respectively]

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Los estudios indican que los efectos gastrointestinales son la causa ms comn de discontinuacin del tratamiento con GLP-1, lo que subraya la importancia de estrategias efectivas de manejo

GLP-1 receptor agonists also reduce the three components of MACE, including CV mortality (reduced by 13%), nonfatal stroke (reduced by 16%) and nonfatal myocardial infarction (reduced by 9%, although the level of significance was not reached)

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