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Do not increase or alter the amount on your own

That means people taking the copycats will soon need to switch to the name-brand version, find another drug, or stop taking anything altogether
In elderly patients with stage 3 CKD, there was no effect of MRA on CV outcomes, potentially because two-thirds of patients stopped spironolactone treatment within 6 months predominantly because they met safety stopping rules (21)

Agree - this is an excellent and important paper
Of course, there may be factors influencing weight-loss outcomes

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