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A recent meta-analysis of randomized trials in obesity and/or diabetes found no increased risk of psychiatric adverse events, with improvements in quality of life, restrained eating, and emotional regulation measures (204)
According to Penn Medicine, the exact cause of NAION isn't fully understood, but it's more common in people who are middle-aged or older, and the shape of someone's optic nerve may even play a role in their risk of eye stroke

Weight loss often becomes noticeable within four to eight weeks, while the most significant results typically occur after several months of consistent treatment

Overall, these signaling cascades increase insulin gene expression, enhance protein synthesis, improve cell survival, and reduce apoptosis

Sin embargo, an no se ha determinado si se puede usar en individuos con diabetes tipo 1
