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GLP-1 receptor agonists (semaglutide, liraglutide) are licensed in the UK for type 2 diabetes and weight management, not lymphoedema

This disruption compromises the membranes barrier function, increasing permeability and fluidity

When to Contact Your Prescriber While most side effects resolve on their own once the body adjusts, the below call for medical attention - Vomiting that persists beyond 48 hours Severe abdominal pain, especially pain that goes all the way to your back (potential sign of pancreatitis) Unable to keep fluids down for more than 24 hours Yellowing of skin or eyes (potential sign of liver issues) Racing heart, palpitations, or chest discomfort Sudden vision changes in one eye (MHRA NAION warning, February 2026) Any signs of an allergic reaction like swelling, rash, difficulty breathing The idea here is not to scare you, but to keep you informed enough so you know what to do once something goes unplanned

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Our bodies responded on completely different timelines, but we ended up in a very similar place by the end