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doi: 10.1128/MCB.00256-14 [DOI] [PMC free article] [PubMed] [Google Scholar] 66

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According to predominant evidence, serotonin in the islets exerts an insulin-upregulating effect primarily via intensifying the signaling of insulin production by cells, promoting the proliferation of cells, reducing the glucagon excretion by cells, and attenuating the oxidative stress in the islets [155159]

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Drug interactions, contraindications, and the need to manage side effects all require ongoing, personalized medical oversight

The STEP Trials (Ozempic/Wegovy) In the STEP 1 trial, participants on semaglutide 2.4 mg lost an average of 14.9% of body weight over 68 weeks
