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To establish the safety of MOTS-c, it is crucial to conduct comprehensive toxicology studies in laboratory animals, including dose-response assessments, long-term exposure evaluations, and investigations into potential adverse effects

2012;130(Suppl 1):S33S36
Introduction As one of the most well-known class B1 G-protein-coupled receptors (GPCRs), the glucagon like peptide-1 receptor (GLP-1R) is a clinically validated drug target for type 2 diabetes and obesity 13

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