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Tirzepatide works by controlling appetite and improving how your body uses insulin, which can result in some weight loss even if you dont make significant adjustments to your eating or exercise habits

This dual mechanism has been associated with enhanced metabolic effects compared to GLP-1 mono-agonists in published head-to-head comparison data

But the reason you are measuring these doses in the first place matters too

Published results have reported mean body weight reductions of approximately 20-22% from baseline at the highest studied doses exceeding published results for semaglutide at comparable timepoints

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