examples of glp 1 drugs GLP-1 Agonists Examples: Which One Wins? GLP-1 Costs Explained: Managing Coverage

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For example, a medication might strongly activate brain GLP-1 receptors for appetite suppression while only partially activating gut receptors that contribute to nausea

Heise T, Mari A, DeVries JH, Urva S, Li J, Pratt EJ, Coskun T, Thomas MK, Mather KJ, Haupt A, et al

Since gastrointestinal adverse effects are rarely severe and tend to diminish over time, they would therefore not be expected to cause a barrier to initiating and continuing treatment for most patients

Trends in discontinuation by indication Side effects were consistently the top reason for stopping treatment for patients receiving ADM and AOM GLP-1s

Obes Surg 34(10):38883896 Kellett J et al (2025) The efficacy of glucagon-like peptide-1 (GLP-1) receptor agonists for insufficient weight loss or regain after metabolic/bariatric surgery: a systematic review and meta-analysis