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[55] This downregulation restores normal leptin signaling pathways (such as the JAK/STAT cascade), effectively re-establishing proper appetite control and reducing energy intake

please follow the advice or guidance of a physician or other healthcare professional

Emerging role of GLP1 agonists in obesity: a comprehensive review of randomised controlled trials

doi: 10.1210/clinem/dgaa337 204 GrillHJ

SSRIs, SNRIs, and the other serotonergic medications listed earlier can cause serotonin syndrome when combined with tesofensine
It's in their relationship with food
