topiramate glp 1 Anti-Obesity medications (Mechanism of Action) – My Endo Consult Topiramate increases hippocampal GLP-1 and

Frias JP, Hsia S, Eyde S, Liu R, Ma X, Konig M, et al

Key takeaways Wegovy (semaglutide) is a GLP-1 drug that is FDA approved for weight loss, cardiovascular risk reduction, and liver disease treatment

Overall, studies indicate that Januvia is generally considered well-tolerated, with a low risk of hypoglycemia when not combined with insulin or sulfonylureas

Further large-scale, randomised controlled trials with longer follow-up are needed before these medications can be considered an evidence-based treatment option for alcohol use disorder

Tarsitano, Maria Grazia, et al

Quick decision guide Max fat loss / prediabetes or T2D: Tirzepatide generally wins for magnitude of weight loss and glycemic control (with careful titration)