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10.1007/s00125-023-06053-9

Overweight adults (BMI 27 kg/m) : With at least one weight-related comorbidity (such as hypertension, type 2 diabetes, dyslipidemia, obstructive sleep apnea, cardiovascular disease, etc.)

I lost 52lbs total and still losing

In mouse models, dual agonism had superior efficacy for weight loss and glucose control compared to a GLP-1RA alone 9 , with additive effects of the GIPR proposed to act through signaling in beta cells 10 , alpha cells 11 , the CNS (central nervous system) 12,13 and adipocytes 14

Footnotes Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article

Here's how to advocate for Wegovy coverage: Ask HR: "Does our plan cover GLP-1 medications for weight management