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Roche reported positive Phase II topline data showing that its once-weekly dual glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide receptor agonist CT-388 achieved substantial, sustained, and dose-dependent weight loss through 48 weeks

These factors include patient age, weight, kidney function, and existing medical conditions, among others

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Combining GLP-1 receptor agonists like semaglutide with metformin represents a evidence-based approach to type 2 diabetes management that addresses multiple metabolic pathways simultaneously
