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Additionally, neither male (Supplemental Figure 1, KP) nor female (Supplemental Figure 1, QV) heterozygous Bbs5 +/ mice displayed any discernable phenotypic changes compared with WT controls

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BPSD-relieving therapy Masupirdine, a selective 5HT6 receptor antagonist with favorable physicochemical properties and absorption, distribution, metabolism, and excretion properties, may have beneficial effects on agitation, aggression, and psychosis in patients with moderate AD [77]

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