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A safety signal worth noting is dysesthesia an abnormal sensation of touch, where normal sensations may feel unusual, tingling, or uncomfortable

Using these medications for a year could result in losing between 3% to 12% more body weight compared to lifestyle changes alone

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Aggressive Bulk (High Surplus or Dirty Bulk): This approach involves a larger calorie surplus , typically +500 to +1000+ calories above TDEE per day

[1] [2] The pharmacological effects of tirzepatide create unique nutritional considerations

doi: 10.3389/fphar.2022.998816 [DOI] [PMC free article] [PubMed] [Google Scholar] 39.Borner T., et al., Glucagon-like peptide-1 in diabetes care: Can glycaemic control be achieved without nausea and vomiting