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Notably, the manufacturer has filed with the FDA for a second indication to reduce MACE in adults with T2D and established cardiovascular disease

Experiments were performed by dispersion of 200 islets, and EphA4 levels in media were measured by EphA4 ELISA (ABclonal, catalog RK06572)

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The candidate showed statistically significant reductions in body weight compared with placebo, with up to 14.7% weight loss after 13 weeks of patients taking the drug