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The reconstitution process requires: Bacteriostatic water (not sterile water, not saline) Alcohol swabs for vial preparation An appropriately sized syringe for accurate measurement Clean workspace with minimal airborne contaminants Direct the bacteriostatic water down the inside wall of the vial rather than spraying it directly onto the powder cake

However, individual variation is substantialsome patients experience minimal symptoms while others require temporary dose reduction or extended titration schedules to maintain tolerability

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Future Trials Need Timing, Reperfusion, and Safety Answers Stroke-dedicated trials need to answer 3 questions before the acute-treatment claim becomes credible