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Rare but serious side effects to watch for: Pancreatitis: Persistent severe abdominal pain radiating to the back, often with nausea and vomiting

(Research has identified mast cells as one of the immune cell types involved in the inflammatory cascades that influence arterial plaque development and lipid-related cardiovascular risk, as I note in my MCAS info page.) In neurological disease , research in animal models of stroke and vascular dementia has shown that GLP-1RAs reduce both microglial activation and neuroinflammation, leading to better protection of the brain from injury and cognitive deterioration

Ozempic should be used cautiously in advanced kidney disease

Kissileff HR, Pi-Sunyer FX, Thornton J, Smith GP

That might mean a small calorie reduction, more steps, better tracking accuracy, improved protein consistency, or a conversation with your provider

When people eat less, protein is often the first thing they miss, which increases the risk of muscle loss, low energy, and a slower metabolism