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Diabetes (2014) 63(10):334658

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doi: 10.1136/bmj.327.7414.557 27 HemaniGZhengJElsworthBWadeKHHaberlandVBairdDet al

Therefore, it was further inferred that exendin-4 might first bind to GLP-1R and act on the PKA pathway, which in turn affects the Wnt/-catenin pathway in the osteoblasts, reduces the expression of sclerostin, and promotes the formation of bone (Kim et al., 2013)

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