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Mental Health You may have seen headlines about GLP-1s and depression or suicidal thoughts

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The answer lies in its unique ability to target two key hormone receptors in your body: GLP-1 and GIP

1 Drugs that cause serotonin toxicity In the brain, serotonin is formed from tryptophan, stored in the presynaptic terminal of a neuron and released into the synapse where it acts on serotonin receptors on the postsynaptic terminal

No head-to-head trial has directly compared these two medications

Concomitant Medications: Evaluate concurrent sulfonylureas or basal insulin (SURPASS-5)
