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A provider has pointed out, The biggest challenge is deciding whether to prescribe medication for patients with BMI near the 30% cutoff, as small variations in weight can significantly impact eligibility. Ethical dilemmas arise when patient expectations are set too high, balancing clinical appropriateness with patient expectations when data foundations are not trustworthy

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Comp Biochem Physiol B Biochem Mol Biol 121(1):4956 Mentlein R, Gallwitz B, Schmidt WE (1993) Dipeptidyl-peptidase IV hydrolyses gastric inhibitory polypeptide, glucagon-like peptide- 1(736)amide, peptide histidine methionine and is responsible for their degradation in human serum

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Slower transit may delay substrate progression to the small intestine, which then shifts the timing of the expected gas peaks

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Some patients may notice increased awareness of breathing during physical activity as they become more active following weight loss

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