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Large amounts of liquid while eating can slow digestion

7 Effect of SANA isomers (3-SANA, 4-SANA) and analog (E-SANA) on creatine induced thermogenesis
Hypertension in CKD: core curriculum 2019

This risk is highest when initiating treatment, adjusting doses, or in patients with pre-existing cardiovascular disease or taking multiple blood pressure medications

The most frequent ones are gastrointestinal, such as nausea, vomiting, diarrhea, and constipation

But if those two meals are large portions of calorie-dense foods, they could easily reach 2,000+ calories without feeling like theyve overeaten